Coupled Model of Blood Volume and Activated Clotting Factor Concentration during Childbirth
نویسندگان
چکیده
منابع مشابه
Activated clotting factors in factor IX concentrates.
The precise quantitation of activated factors in human factor IX concentrates has been accomplished with the use of recently developed, specific assays for factors IXa, Xa, and thrombin. The assay for factor IXa, which measures the initial rate of 3H-factor-X activation, was shown to be specific for factor IXa in the concentrates. Activated factor IX concentrates contained 1.0-2.3 microgram/ml ...
متن کاملMeasured by Activated Clotting Time and Factor Xa Inhibition
The effect of hypothermia on heparin anticoagulation was studied using (siliceous earth) activated clotting time (ACT) measured by the modified Hattersley technique and anti-factor Xa assay measured by the modified Teien technique during cardiopulmonary bypass (CPB). Seventeen adult patients with normal blood coagulation function undergoing their first time coronary artery bypass grafting surge...
متن کاملCleavage of blood coagulation factor XIII and fibrinogen by thrombin during in vitro clotting.
Thrombin cleavage of blood coagulation Factor XIII (a2b2) and fibrinogen was studied during in vitro clotting to determine the physiologic sequence of these events. First, the time course of fibrin formation and cleavage of Factor XIII was measured in platelet-rich plasma. Cleavage of fibrinogen was measured by using a radioimmunoassay for fibrinopeptide A. Conversion of trace amounts of radioi...
متن کاملRelationship between secretion of platelet Factor 4 and thrombin generation during in vitro blood clotting.
We have studied the effects of both impaired prothrombin activation and direct inhibition of thrombin on the platelet release reaction in clotting blood to determine the role of thrombin in this process. In blood from two patients with congenital Factor V deficiency, prothrombin activation during spontaneous in vitro clotting was delayed and decreased. Secretion of platelet Factor 4 was also de...
متن کاملThrombin generation and secretion of platelet Factor 4 during blood clotting.
We have studied the platelet release reaction and thrombin generation during the spontaneous clotting of whole blood in vitro. Both thrombin formation and secretion of platelet Factor 4 were detected at least 12 min before clotting (clotting time, 22--26 min). Initially, at low thrombin concentrations (2--5 ng/ml), there is a small increase in plasma platelet Factor 4 (less than 1% of the amoun...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: IFAC-PapersOnLine
سال: 2018
ISSN: 2405-8963
DOI: 10.1016/j.ifacol.2018.09.038